During World War II, Henry Beecher, an anesthesiologist serving in the U.S. Army, noticed that 32% of the soldiers he treated for horrific battle wounds felt no pain. A further 44% experienced only slight or mild discomfort, despite the fact they had shrapnel embedded in their bodies. Beecher hypothesized that the euphoria of surviving battle resulted in the release of a natural painkiller. When morphine was running low in Europe, Beecher thought he could harness the mind’s seeming ability to produce natural painkillers in a different way by injecting soldiers who were about to undergo surgery with a simple saline solution, while telling the soldiers they were receiving morphine. About 90% of these patients underwent the surgery with little or no pain.